Olivier Cornelis

Olivier Cornelis

Psychiatry resident & self-taught developer / data scientist.

Tools

On this page, I try to keep track of resources I think can be useful to psychiatry residents. In each section, I try my best to order by most important first.

Helper tools

Some of these are tools I made; fuller descriptions are on PROJECTS. (To be clear: no patient data is ever involved, not even anonymized, and not even on servers I run myself.)

  • I made psychiatheque, a search over psychiatry guidelines and recommendations that shows the matching passage on its original page, so you read the source itself rather than a summary. Public instance, source of the software.

  • I made justelesRCP to look up drug data faster: the official French RCP sheets (ANSM/BDPM/EMA open data, around 15,600 medications) as a fast, ad-free site with AI-based plain-language search. Source.

  • I made neurarium, a 3D neuroanatomy atlas covering regions, projections, receptors, psychiatric drugs and their metabolism, with a provenance grade on every entry so you can tell what is solid and what is not. Public instance, source.

    neurarium

  • At pdf.olicorne.org I host PDF tools (rotate, remove pages, split, merge, text recognition, etc.) that run entirely in your browser: your PDF never reaches a server. It is a BentoPDF instance.

  • I made WebSend to scan documents without a flatbed scanner: open the page on your phone and on the computer, and the photo transfers directly between the two, end-to-end encrypted. Public instance, source.

  • I made Parakeet Web to turn speech into text on locked-down machines: the model runs in the browser itself, so nothing is sent anywhere. It can load a French medical finetune I trained (model, from an open dataset I built for it): 7-8x fewer errors than the base model on technical medical vocabulary, with ordinary speech essentially unchanged. Both are freely licensed, so any team or vendor can reuse them rather than rebuild them. Public instance, source.

Prescribing

General drug information

Enzymatic interactions

  • PharmFreq: nice widgets mapping the worldwide frequency of pharmacogenetic variants. Handy to weigh how likely a given metabolizer phenotype is for a patient depending on where their family comes from.
  • Was recommended to me: DDI-Predictor, by the Hospices Civils de Lyon and / or University Claude Bernard Lyon I, Lyon, France.
  • Seems rather complete and was recommended to me: ClinPGx (formerly PharmGKB).
    • I noticed at least once a pretty wild oversimplification: the text on ClinPGx mentioned one cytochrome as being the main one, while the source actually explained that this one was actually the one that bound to the molecule the most but because it was less present it was actually not the main metabolizer of the given drug.
    • My conclusion is that the most reliable way to check enzymatic drug pathways is to use ClinPGx to reason but then read all the underlying sources’ abstracts to reduce the chances of this happening again.
  • Drug Interaction Flockhart Table (main table, search): seemed promising, seems to cite sources extensively but not yet sure about exhaustivity, 2021 initially but updated twice a year apparently.
    • But: does not mention lamotrigine, and only a subset of the known venlafaxine interactions.
  • In French, from Switzerland:
  • SuperCYPsPred, 2020: this research website seemed to contain promising tools but they seemed to handle pretty badly their HTTPS certificates.

Adverse effects

  • VigiAccess, by the WHO (VigiBase data access): side effects of medications as reported worldwide, for example to check whether a medication has already been involved in cases of catatonia. These are spontaneous reports, so they do not tell how frequent an effect is.

Formulas, clinical scales and scores

Clinical

Psychotherapy

  • TCC MontrĂ©al: a great French-language resource on cognitive behavioral therapy (CBT).

Misc