On this page, I try to keep track of resource I think can be useful to psychiatry residents. In each section, I try my best to order by most important first.

Helper tools

Some of these are tools I made; fuller descriptions are on PROJECTS. (To be clear: no patient data is ever involved, not even anonymized, and not even on servers I run myself.)

• I made neurarium, a 3D neuroanatomy atlas covering regions, projections, receptors and psychiatric drugs, with a provenance grade on every entry so you can tell what is solid and what is not. Public instance, source.

  

• I made WebSend to scan documents without a flatbed scanner: open the page on your phone and on the computer, and the photo transfers directly between the two, end-to-end encrypted. Public instance, source.

• I made Parakeet Web to turn speech into text on locked-down machines: the model runs in the browser itself, so nothing is sent anywhere. It can load a French medical finetune I trained (model, from an open dataset I built for it): 7-8x fewer errors than the base model on technical medical vocabulary, with ordinary speech essentially unchanged. Both are freely licensed, so any team or vendor can reuse them rather than rebuild them. Public instance, source.

• I made justelesRCP to look up drug data faster: the official French RCP sheets (ANSM/BDPM/EMA open data, around 15,600 medications) as a fast, ad-free site with AI-based plain-language search. Source.

Enzymatic interaction

• Was recommended to me: DDI-Predictor, by the Hospices Civils de Lyon and / or University Claude Bernard Lyon I, Lyon, France.
• Seems rather complete and was recommended to me: ClinPGx (formerly PharmGKB).
  • I noticed at least once a pretty wild oversimplification: the text on ClinPGx mentioned one cytochrome as being the main one, while the source actually explained that this one was actually the one that bound to the molecule the most but because it was less present it was actually not the main metabolizer of the given drug.
  • My conclusion is that the most reliable way to check enzymatic drug pathways is to use ClinPGx to reason but then read all the underlying sources’s abstracts to reduce the chances of this happening again.
• Seemed promising, seems to cite sources extensively but not yet sure about exhaustivity, 2021 initially but updated twice a year apparently:
  • But: does not mention lamotrigin, and only a subset of the known venlafaxin interactions.
  • Drug Interaction Flockhart Table
    • https://drug-interactions.medicine.iu.edu/main-table
    • https://drug-interactions.medicine.iu.edu/search
• In French from switzerland:
  • Good table, was often recommended to me, 2017: Interactions médicamenteuses, cytochromes P450 et P-glycoprotéine (Pgp)
  • Only about antidepressants, 2013: Dosage plasmatique des médicaments antidépresseurs
• This research website seemed to contain promising tools but they seemed to handle pretty badly their HTTPS certificates, 2020:
  • https://insilico-cyp.charite.de/SuperCYPsPred/

General drug information

• ClinPGx (formerly PharmGKB) (described above).
• The Resume des Caracteristiques du Produit accessed through the Base de donnee publique du medicament.
• Vidal as well as Hoptimal Vidal (“hospital” version).
• To know which drugs is unavailable to patients: Disponibilité des produits de santé

Formulas and Scores

• QTc calculation by PsychoPharma.fr.